Intrauterine Insemination (IUI Treatment)

It is a simple technique that involves the deposition of a washed semen sample into the woman’s uterus around the time of ovulation.

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Explanation

Intrauterine insemination (IUI) involves a laboratory procedure to separate fast-moving sperm from more sluggish or non-moving sperm. The fast-moving sperms are then placed into the woman’s womb close to the time of ovulation when the egg is released from the ovary in the middle of the monthly cycle. It is used as an intermediate level intervention prior to proceeding to in vitro fertilization (IVF). 

It is essential that your fallopian tubes are known to be open and healthy before the IUI process begins. The second essential requirement is that there is no severe problem with sperm numbers or sperm quality. The intrauterine insemination success rate is up to 12- 20% per cycle. It is recommended that at least 3-4 cycles of treatment are attempted before considering other options.

Indications

  • Ejaculatory dysfunction (including sexual dysfunction and impotence)
  • Severe vaginismus (Where woman is unable to have an intercourse)
  • Cervical factor infertility 
  • Mildly Low sperm count and motility 
  • Unexplained infertility 
  • Stage I or II endometriosis
  • Absent or defective ovulation as in PCOS
  • Absent sperms (azoospermia) – For Donor sperm insemination

Did You Know?

The intrauterine insemination success rate is up to 12- 20% per cycle

Treatment Protocol

Ovulation Induced & Semen preparation

The woman begins taking oral or injectable medication to stimulate the growth and maturation of her eggs. Oral medication is taken for 5 days and injectable medication is usually taken for 8-12 days based on how the ovaries respond.

Ovulation Induced & Semen Preparation

Once a “ripe” egg is present, a patient receives a “trigger shot” , that causes ovulation within 36 hours. This helps to time ovulation & identify the right time to do IUI. IUI is done 34 -38 hours after the injection. Male partner provides semen sample. This is prepared by washing in a way that only the highly motile sperms are separated out for use thus increasing chance of pregnancy.

Insemination Procedure & Followup

Just like a routine pelvic exam, a woman lies on an exam table. The sperm sample is injected into the uterus through a thin, long, flexible catheter. The entire process is virtually painless and takes seconds to complete. You would be expected to lie for 20 minutes after the procedure. A pregnancy test is advised 15 days later.

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Our Success Story

I can’t thank Dr Surveen enough for all the kindness and professionalism shown throughout our treatment. I felt a personal connection with all the staff members as each was so caring and made me feel so comfortable at all times.

We had consulted 3 doctors (who performed 4 unsuccessful IUI’s) before meeting Dr. Surveen for discussing our ‘unexplained not able to conceive issue’. She is so gentle and answered our queries with such grace and patience that we got confidence in our first meeting.

We came to meet Dr.Surveen only for a 2nd opinion, but talking to her about our journey and the way she comforted us by giving us confidence made us decide to go for our IVF treatment under her supervision only.


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Frequently Asked Questions

Besides the number of sperm, the percentage with rapid forward-progressive motility and with normal morphology at the time of insemination are important to know. If the functional sperm count (number with normal morphology and rapid forward-progressive motility) exceeds 5 million; chances for pregnancy with well-timed IUI are excellent.

Normal, healthy sperm live approximately 48-72 hours. (Abnormal sperm may have a shorter life, which may vary according to sperm health.) At IVF India we know that washed sperm can survive in the IVF incubator for up to 72 hours. That would be considered the upper practical limit.

Eggs are able to be fertilized for about 12-24 hours after ovulation. The older the woman, the shorter this time becomes.

Once a patient has had 3-6 IUI cycles , they might consider moving to IVF as the chance of a successful IUI cycle is reduced.

Donor insemination (DI) uses sperm from a donor to help the woman become pregnant. IUI donor sperm in case –

  • Male partner is unable to produce sperm
  • Male partner’s sperm count or quality is so poor that it is unlikely to result in the conception of a baby unless IVF/intra-cytoplasmic sperm injection (ICSI) is carried out, for which the patient is unwilling
  • Male partner has a high risk of passing on an inherited disease and patient does not want an IVF with PGD ( preimplantation genetic diagnosis)
  • Male partner is chronically infected with HIV/ Hepatitis B in which case washing the sperm and inserting in uterus decreases virus in semen and hence decreases the chance of infection.
  • Patient is single and does not have a male partner

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